Cargando…

KIR genotype distribution among patients with multiple myeloma: Higher prevalence of KIR 2DS4 and KIR 2DS5 genes

INTRODUCTION: Natural killer (NK) cells possess an antitumor activity against multiple myeloma cells proven by the susceptibility of plasmocytes to NK lysis. In the early stage of MM, the killing of MM cells is mediated by natural cytotoxicity receptors (NRC) and NKG2D-dependent pathway, while in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoteit, R., Bazarbachi, A., Antar, A., Salem, Z., Shammaa, D., Mahfouz, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287873/
https://www.ncbi.nlm.nih.gov/pubmed/25606456
http://dx.doi.org/10.1016/j.mgene.2014.09.008