5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion

Nonsense-mediated RNA decay (NMD) is an RNA-based quality control mechanism that eliminates transcripts bearing premature translation termination codons (PTC). Approximately, one-third of all inherited disorders and some forms of cancer are caused by nonsense or frame shift mutations that introduce...

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Detalles Bibliográficos
Autores principales: Bhuvanagiri, Madhuri, Lewis, Joe, Putzker, Kerstin, Becker, Jonas P, Leicht, Stefan, Krijgsveld, Jeroen, Batra, Richa, Turnwald, Brad, Jovanovic, Bogdan, Hauer, Christian, Sieber, Jana, Hentze, Matthias W, Kulozik, Andreas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287977/
https://www.ncbi.nlm.nih.gov/pubmed/25319547
http://dx.doi.org/10.15252/emmm.201404461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287977/
https://www.ncbi.nlm.nih.gov/pubmed/25319547
http://dx.doi.org/10.15252/emmm.201404461

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