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MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

The heart requires a continuous supply of energy but has little capacity for energy storage and thus relies on exogenous metabolic sources. We previously showed that cardiac MED13 modulates systemic energy homeostasis in mice. Here, we sought to define the extra-cardiac tissue(s) that respond to car...

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Detalles Bibliográficos
Autores principales: Baskin, Kedryn K, Grueter, Chad E, Kusminski, Christine M, Holland, William L, Bookout, Angie L, Satapati, Santosh, Kong, Y Megan, Burgess, Shawn C, Malloy, Craig R, Scherer, Philipp E, Newgard, Christopher B, Bassel-Duby, Rhonda, Olson, Eric N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287978/
https://www.ncbi.nlm.nih.gov/pubmed/25422356
http://dx.doi.org/10.15252/emmm.201404218