Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors

The nerve growth factor (NGF) pathway has been shown to play a key role in pain treatment. Recently, a systems pharmacology model has been proposed that can aid in the identification and validation of drug targets in the NGF pathway. However, this model did not include the role of the p75 receptor,...

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Detalles Bibliográficos
Autores principales: Toni, T, Dua, P, van der Graaf, P H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288001/
https://www.ncbi.nlm.nih.gov/pubmed/25470184
http://dx.doi.org/10.1038/psp.2014.48