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DEEP: a general computational framework for predicting enhancers

Transcription regulation in multicellular eukaryotes is orchestrated by a number of DNA functional elements located at gene regulatory regions. Some regulatory regions (e.g. enhancers) are located far away from the gene they affect. Identification of distal regulatory elements is a challenge for the...

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Detalles Bibliográficos
Autores principales: Kleftogiannis, Dimitrios, Kalnis, Panos, Bajic, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288148/
https://www.ncbi.nlm.nih.gov/pubmed/25378307
http://dx.doi.org/10.1093/nar/gku1058