Topological constraints strongly affect chromatin reconstitution in silico

The fundamental building block of chromatin, and of chromosomes, is the nucleosome, a composite material made up from DNA wrapped around a histone octamer. In this study we provide the first computer simulations of chromatin self-assembly, starting from DNA and histone proteins, and use these to und...

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Detalles Bibliográficos
Autores principales: Brackley, C.A., Allan, J., Keszenman-Pereyra, D., Marenduzzo, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288149/
https://www.ncbi.nlm.nih.gov/pubmed/25432958
http://dx.doi.org/10.1093/nar/gku1085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288149/
https://www.ncbi.nlm.nih.gov/pubmed/25432958
http://dx.doi.org/10.1093/nar/gku1085

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