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HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to th...

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Detalles Bibliográficos
Autores principales: Chamontin, Célia, Rassam, Patrice, Ferrer, Mireia, Racine, Pierre-Jean, Neyret, Aymeric, Lainé, Sébastien, Milhiet, Pierre-Emmanuel, Mougel, Marylène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288153/
https://www.ncbi.nlm.nih.gov/pubmed/25488808
http://dx.doi.org/10.1093/nar/gku1232