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Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin

High-throughput sequencing reveals an abundance of microRNA-sized fragments derived from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by their co-precipitation with Argonaute, the microRNA effector protein, though the extent to which they suppress gene expressio...

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Detalles Bibliográficos
Autores principales: Thomson, Daniel W., Pillman, Katherine A., Anderson, Matthew L., Lawrence, David M., Toubia, John, Goodall, Gregory J., Bracken, Cameron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288155/
https://www.ncbi.nlm.nih.gov/pubmed/25452337
http://dx.doi.org/10.1093/nar/gku1242