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Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin
High-throughput sequencing reveals an abundance of microRNA-sized fragments derived from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by their co-precipitation with Argonaute, the microRNA effector protein, though the extent to which they suppress gene expressio...
Autores principales: | Thomson, Daniel W., Pillman, Katherine A., Anderson, Matthew L., Lawrence, David M., Toubia, John, Goodall, Gregory J., Bracken, Cameron P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288155/ https://www.ncbi.nlm.nih.gov/pubmed/25452337 http://dx.doi.org/10.1093/nar/gku1242 |
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