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Site-specific fluorescence dynamics in an RNA ‘thermometer’ reveals the role of ribosome binding in its temperature-sensitive switch function

RNA thermometers control the translation of several heat shock and virulence genes by their temperature-sensitive structural transitions. Changes in the structure and dynamics of MiniROSE RNA, which regulates translation in the temperature range of 20–45°C, were studied by site specifically replacin...

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Detalles Bibliográficos
Autores principales: Narayan, Satya, Kombrabail, Mamta H., Das, Sudipta, Singh, Himanshu, Chary, Kandala V. R., Rao, Basuthkar J., Krishnamoorthy, Guruswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288164/
https://www.ncbi.nlm.nih.gov/pubmed/25477380
http://dx.doi.org/10.1093/nar/gku1264