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Estimating binding properties of transcription factors from genome-wide binding profiles

The binding of transcription factors (TFs) is essential for gene expression. One important characteristic is the actual occupancy of a putative binding site in the genome. In this study, we propose an analytical model to predict genomic occupancy that incorporates the preferred target sequence of a...

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Detalles Bibliográficos
Autores principales: Zabet, Nicolae Radu, Adryan, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288167/
https://www.ncbi.nlm.nih.gov/pubmed/25432957
http://dx.doi.org/10.1093/nar/gku1269