Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance

The RNA component of human telomerase (hTR) localizes to Cajal bodies, and it has been proposed that Cajal bodies play a role in the assembly of telomerase holoenzyme and telomerase trafficking. Here, the role of Cajal bodies was examined in Human cells deficient of coilin (i.e. coilin-knockout (KO)...

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Detalles Bibliográficos
Autores principales: Chen, Yanlian, Deng, Zhiqiang, Jiang, Shuai, Hu, Qian, Liu, Haiying, Songyang, Zhou, Ma, Wenbin, Chen, Shi, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288172/
https://www.ncbi.nlm.nih.gov/pubmed/25477378
http://dx.doi.org/10.1093/nar/gku1277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288172/
https://www.ncbi.nlm.nih.gov/pubmed/25477378
http://dx.doi.org/10.1093/nar/gku1277

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