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Flexibility and structural conservation in a c-KIT G-quadruplex
A quadruplex sequence from the promoter region of the c-KIT gene forms a stable quadruplex, as characterized by crystallographic and NMR methods. Two new crystal structures are reported here, together with molecular dynamics simulation studies on these quadruplex crystal structures and an NMR struct...
Autores principales: | Wei, Dengguo, Husby, Jarmila, Neidle, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288176/ https://www.ncbi.nlm.nih.gov/pubmed/25452341 http://dx.doi.org/10.1093/nar/gku1282 |
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