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Bacterial initiators form dynamic filaments on single-stranded DNA monomer by monomer

DNA replication initiation is mediated across all domains of life by initiator proteins oligomerizing at replication origins. Recently, it was shown that initiators can directly bind single-stranded DNA (ssDNA) and thus might enhance origin melting. In this study, we used single-molecule fluorescenc...

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Detalles Bibliográficos
Autores principales: Cheng, Hsin-Mei, Gröger, Philip, Hartmann, Andreas, Schlierf, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288177/
https://www.ncbi.nlm.nih.gov/pubmed/25477384
http://dx.doi.org/10.1093/nar/gku1284