Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA

The predictable 3D structure of double-stranded DNA renders it ideally suited as a template for the bottom-up design of functionalized nucleic acid-based active sites. We here explore the use of a 14mer DNA duplex as a scaffold for the precise and predictable positioning of catalytic functionalities...

Descripción completa

Detalles Bibliográficos
Autores principales: Buyst, Dieter, Gheerardijn, Vicky, Fehér, Krisztina, Van Gasse, Bjorn, Van Den Begin, Jos, Martins, José C., Madder, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288195/
https://www.ncbi.nlm.nih.gov/pubmed/25520197
http://dx.doi.org/10.1093/nar/gku1306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288195/
https://www.ncbi.nlm.nih.gov/pubmed/25520197
http://dx.doi.org/10.1093/nar/gku1306

Ejemplares similares