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Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA

The predictable 3D structure of double-stranded DNA renders it ideally suited as a template for the bottom-up design of functionalized nucleic acid-based active sites. We here explore the use of a 14mer DNA duplex as a scaffold for the precise and predictable positioning of catalytic functionalities...

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Detalles Bibliográficos
Autores principales:	Buyst, Dieter, Gheerardijn, Vicky, Fehér, Krisztina, Van Gasse, Bjorn, Van Den Begin, Jos, Martins, José C., Madder, Annemieke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288195/ https://www.ncbi.nlm.nih.gov/pubmed/25520197 http://dx.doi.org/10.1093/nar/gku1306

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