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Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation

The cellular function of the cancer-associated RNA-binding protein La has been linked to translation of viral and cellular mRNAs. Recently, we have shown that the human La protein stimulates IRES-mediated translation of the cooperative oncogene CCND1 in cervical cancer cells. However, there is littl...

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Detalles Bibliográficos
Autores principales: Kuehnert, Julia, Sommer, Gunhild, Zierk, Avery W., Fedarovich, Alena, Brock, Alexander, Fedarovich, Dzmitry, Heise, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288197/
https://www.ncbi.nlm.nih.gov/pubmed/25520193
http://dx.doi.org/10.1093/nar/gku1309