Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches

G-quadruplexes (G4) are intricate RNA structures found throughout the transcriptome. Because they are associated with a variety of biological cellular mechanisms, these fascinating structural motifs are seen as potential therapeutic targets against many diseases. While screening of chemical compound...

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Detalles Bibliográficos
Autores principales: Rouleau, Samuel G., Beaudoin, Jean-Denis, Bisaillon, Martin, Perreault, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288198/
https://www.ncbi.nlm.nih.gov/pubmed/25510493
http://dx.doi.org/10.1093/nar/gku1311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288198/
https://www.ncbi.nlm.nih.gov/pubmed/25510493
http://dx.doi.org/10.1093/nar/gku1311

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