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Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches
G-quadruplexes (G4) are intricate RNA structures found throughout the transcriptome. Because they are associated with a variety of biological cellular mechanisms, these fascinating structural motifs are seen as potential therapeutic targets against many diseases. While screening of chemical compound...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288198/ https://www.ncbi.nlm.nih.gov/pubmed/25510493 http://dx.doi.org/10.1093/nar/gku1311 |