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Identifying causal regulatory SNPs in ChIP-seq enhancers

Thousands of non-coding SNPs have been linked to human diseases in the past. The identification of causal alleles within this pool of disease-associated non-coding SNPs is largely impossible due to the inability to accurately quantify the impact of non-coding variation. To overcome this challenge, w...

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Detalles Bibliográficos
Autores principales: Huang, Di, Ovcharenko, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288203/
https://www.ncbi.nlm.nih.gov/pubmed/25520196
http://dx.doi.org/10.1093/nar/gku1318