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Distinct Effects of Methotrexate and Etanercept on the B Cell Compartment in Patients With Juvenile Idiopathic Arthritis

OBJECTIVE: B cells have been shown to play an important role in the pathogenesis of rheumatoid arthritis and juvenile idiopathic arthritis (JIA). Current treatments include the disease-modifying antirheumatic drugs methotrexate (MTX) and tumor necrosis factor α inhibition with etanercept. This study...

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Detalles Bibliográficos
Autores principales: Glaesener, Stephanie, Quách, Tâm D, Onken, Nils, Weller-Heinemann, Frank, Dressler, Frank, Huppertz, Hans-Iko, Thon, Angelika, Meyer-Bahlburg, Almut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288311/
https://www.ncbi.nlm.nih.gov/pubmed/24909567
http://dx.doi.org/10.1002/art.38736