A protective role of ciglitazone in ox-LDL-induced rat microvascular endothelial cells via modulating PPARγ-dependent AMPK/eNOS pathway

Thiazolidinediones, the antidiabetic agents such as ciglitazone, has been proved to be effective in limiting atherosclerotic events. However, the underlying mechanism remains elucidative. Ox-LDL receptor-1 (LOX-1) plays a central role in ox-LDL-mediated atherosclerosis via endothelial nitric oxide s...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Wang, Shijun, Li, Bingyu, Sun, Aijun, Zou, Yunzeng, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288353/
https://www.ncbi.nlm.nih.gov/pubmed/25388834
http://dx.doi.org/10.1111/jcmm.12463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288353/
https://www.ncbi.nlm.nih.gov/pubmed/25388834
http://dx.doi.org/10.1111/jcmm.12463

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