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A protective role of ciglitazone in ox-LDL-induced rat microvascular endothelial cells via modulating PPARγ-dependent AMPK/eNOS pathway
Thiazolidinediones, the antidiabetic agents such as ciglitazone, has been proved to be effective in limiting atherosclerotic events. However, the underlying mechanism remains elucidative. Ox-LDL receptor-1 (LOX-1) plays a central role in ox-LDL-mediated atherosclerosis via endothelial nitric oxide s...
Autores principales: | Xu, Lei, Wang, Shijun, Li, Bingyu, Sun, Aijun, Zou, Yunzeng, Ge, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288353/ https://www.ncbi.nlm.nih.gov/pubmed/25388834 http://dx.doi.org/10.1111/jcmm.12463 |
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