ASPP2 attenuates triglycerides to protect against hepatocyte injury by reducing autophagy in a cell and mouse model of non-alcoholic fatty liver disease

ASPP2 is a pro-apoptotic member of the p53 binding protein family. ASPP2 has been shown to inhibit autophagy, which maintains energy balance in nutritional deprivation. We attempted to identify the role of ASPP2 in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In a NAFLD cell model,...

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Detalles Bibliográficos
Autores principales: Xie, Fang, Jia, Lin, Lin, Minghua, Shi, Ying, Yin, Jiming, Liu, Yin, Chen, Dexi, Meng, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288359/
https://www.ncbi.nlm.nih.gov/pubmed/25256142
http://dx.doi.org/10.1111/jcmm.12364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288359/
https://www.ncbi.nlm.nih.gov/pubmed/25256142
http://dx.doi.org/10.1111/jcmm.12364

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