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BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

The process of vascular calcification shares many similarities with that of physiological skeletal mineralization, and involves the deposition of hydroxyapatite crystals in arteries. However, the cellular mechanisms responsible have yet to be fully explained. Bone morphogenetic protein (BMP-9) has b...

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Detalles Bibliográficos
Autores principales: Zhu, Dongxing, Mackenzie, Neil Charles Wallace, Shanahan, Catherine M, Shroff, Rukshana C, Farquharson, Colin, MacRae, Vicky Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288360/
https://www.ncbi.nlm.nih.gov/pubmed/25297851
http://dx.doi.org/10.1111/jcmm.12373