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BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway
The process of vascular calcification shares many similarities with that of physiological skeletal mineralization, and involves the deposition of hydroxyapatite crystals in arteries. However, the cellular mechanisms responsible have yet to be fully explained. Bone morphogenetic protein (BMP-9) has b...
Autores principales: | Zhu, Dongxing, Mackenzie, Neil Charles Wallace, Shanahan, Catherine M, Shroff, Rukshana C, Farquharson, Colin, MacRae, Vicky Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288360/ https://www.ncbi.nlm.nih.gov/pubmed/25297851 http://dx.doi.org/10.1111/jcmm.12373 |
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