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Adeno-associated viral vectors do not efficiently target muscle satellite cells

Adeno-associated viral (AAV) vectors are becoming an important tool for gene therapy of numerous genetic and other disorders. Several recombinant AAV vectors (rAAV) have the ability to transduce striated muscles in a variety of animals following intramuscular and intravascular administration, and ha...

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Detalles Bibliográficos
Autores principales: Arnett, Andrea LH, Konieczny, Patryk, Ramos, Julian N, Hall, John, Odom, Guy, Yablonka-Reuveni, Zipora, Chamberlain, Joel R, Chamberlain, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288464/
https://www.ncbi.nlm.nih.gov/pubmed/25580445
http://dx.doi.org/10.1038/mtm.2014.38