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A framework for modelling gene regulation which accommodates non-equilibrium mechanisms
BACKGROUND: Gene regulation has, for the most part, been quantitatively analysed by assuming that regulatory mechanisms operate at thermodynamic equilibrium. This formalism was originally developed to analyse the binding and unbinding of transcription factors from naked DNA in eubacteria. Although w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288563/ https://www.ncbi.nlm.nih.gov/pubmed/25475875 http://dx.doi.org/10.1186/s12915-014-0102-4 |