Cargando…

A framework for modelling gene regulation which accommodates non-equilibrium mechanisms

BACKGROUND: Gene regulation has, for the most part, been quantitatively analysed by assuming that regulatory mechanisms operate at thermodynamic equilibrium. This formalism was originally developed to analyse the binding and unbinding of transcription factors from naked DNA in eubacteria. Although w...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahsendorf, Tobias, Wong, Felix, Eils, Roland, Gunawardena, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288563/
https://www.ncbi.nlm.nih.gov/pubmed/25475875
http://dx.doi.org/10.1186/s12915-014-0102-4