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Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae

Bacterial biofilms are estimated to be associated with over 65 percent of all nosocomial infections. However, no therapeutics have been approved by the FDA which directly mediate biofilm formation or persistence. Herein we report oxazine 25 as a highly potent inhibitor, disperser and in the presence...

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Detalles Bibliográficos
Autores principales: Warner, Christopher J. A., Cheng, Andrew T., Yildiz, Fitnat H., Linington, Roger G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288701/
https://www.ncbi.nlm.nih.gov/pubmed/25479128
http://dx.doi.org/10.1039/c4cc07003h