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What Makes a Protein Sequence a Prion?
Typical amyloid diseases such as Alzheimer's and Parkinson's were thought to exclusively result from de novo aggregation, but recently it was shown that amyloids formed in one cell can cross-seed aggregation in other cells, following a prion-like mechanism. Despite the large experimental e...
Autores principales: | Sabate, Raimon, Rousseau, Frederic, Schymkowitz, Joost, Ventura, Salvador |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288708/ https://www.ncbi.nlm.nih.gov/pubmed/25569335 http://dx.doi.org/10.1371/journal.pcbi.1004013 |
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