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Hyperreactive Onchocerciasis is Characterized by a Combination of Th17-Th2 Immune Responses and Reduced Regulatory T Cells

Clinical manifestations in onchocerciasis range from generalized onchocerciasis (GEO) to the rare but severe hyperreactive (HO)/sowda form. Since disease pathogenesis is associated with host inflammatory reactions, we investigated whether Th17 responses could be related to aggravated pathology in HO...

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Detalles Bibliográficos
Autores principales: Katawa, Gnatoulma, Layland, Laura E., Debrah, Alex Y., von Horn, Charlotte, Batsa, Linda, Kwarteng, Alexander, Arriens, Sandra, W. Taylor, David, Specht, Sabine, Hoerauf, Achim, Adjobimey, Tomabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288720/
https://www.ncbi.nlm.nih.gov/pubmed/25569210
http://dx.doi.org/10.1371/journal.pntd.0003414