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A Discrete Transition Zone Organizes the Topological and Regulatory Autonomy of the Adjacent Tfap2c and Bmp7 Genes

Despite the well-documented role of remote enhancers in controlling developmental gene expression, the mechanisms that allocate enhancers to genes are poorly characterized. Here, we investigate the cis-regulatory organization of the locus containing the Tfap2c and Bmp7 genes in vivo, using a series...

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Detalles Bibliográficos
Autores principales: Tsujimura, Taro, Klein, Felix A., Langenfeld, Katja, Glaser, Juliane, Huber, Wolfgang, Spitz, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288730/
https://www.ncbi.nlm.nih.gov/pubmed/25569170
http://dx.doi.org/10.1371/journal.pgen.1004897