Cargando…
A Discrete Transition Zone Organizes the Topological and Regulatory Autonomy of the Adjacent Tfap2c and Bmp7 Genes
Despite the well-documented role of remote enhancers in controlling developmental gene expression, the mechanisms that allocate enhancers to genes are poorly characterized. Here, we investigate the cis-regulatory organization of the locus containing the Tfap2c and Bmp7 genes in vivo, using a series...
Autores principales: | Tsujimura, Taro, Klein, Felix A., Langenfeld, Katja, Glaser, Juliane, Huber, Wolfgang, Spitz, François |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288730/ https://www.ncbi.nlm.nih.gov/pubmed/25569170 http://dx.doi.org/10.1371/journal.pgen.1004897 |
Ejemplares similares
-
Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c–Bmp7 locus
por: Tsujimura, Taro, et al.
Publicado: (2018) -
Functional and topological characteristics of mammalian regulatory domains
por: Symmons, Orsolya, et al.
Publicado: (2014) -
Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis
por: Timberlake, Andrew T., et al.
Publicado: (2019) -
Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling
por: Kantarci, Husniye, et al.
Publicado: (2015) -
Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum
por: Zainolabidin, Norliyana, et al.
Publicado: (2017)