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Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signaling pathway

Neuronal activity regulates the phosphorylation states at multiple sites on MeCP2 in postmitotic neurons. The precise control of the phosphorylation status of MeCP2 in neurons is critical for the normal development and function of the mammalian brain. However, it is unknown whether phosphorylation a...

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Detalles Bibliográficos
Autores principales: Li, Hongda, Zhong, Xiaofen, Chau, Kevin Fongching, Santistevan, Nicholas J., Guo, Weixiang, Kong, Guangyao, Li, Xuekun, Kadakia, Mitul, Masliah, Jamie, Chi, Jingyi, Jin, Peng, Zhang, Jing, Zhao, Xinyu, Chang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288926/
https://www.ncbi.nlm.nih.gov/pubmed/25420914
http://dx.doi.org/10.1038/ncomms6601