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Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development

In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of complement activation in placenta and foetal brain in vivo in utero. Using this method, we found that anti-complement C3-targeted ultrasmall superparamagnetic iron oxide (USPIO) nanopartic...

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Detalles Bibliográficos
Autores principales: Girardi, G, Fraser, J, Lennen, R, Vontell, R, Jansen, M, Hutchison, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288949/
https://www.ncbi.nlm.nih.gov/pubmed/25245499
http://dx.doi.org/10.1038/mp.2014.110