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Versatile and enhanced tumour modelling in mice via somatic cell transduction

Genetically engineered mouse (GEM) models of cancer currently comprise the most accurate way to experimentally recapitulate the human disease in the laboratory. Given recent advances in genomics and genetic screens, however, as well as an increasing urgency for the translation of effective preclinic...

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Detalles Bibliográficos
Autores principales: Rodriguez, Esther, Mannion, Liz, D'Santos, Paula, Griffiths, Meryl, Arends, Mark J, Brindle, Kevin M, Lyons, Scott K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288983/
https://www.ncbi.nlm.nih.gov/pubmed/24307564
http://dx.doi.org/10.1002/path.4313