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Characterization of a Nudix hydrolase from Deinococcus radiodurans with a marked specificity for (deoxy)ribonucleoside 5'-diphosphates

BACKGROUND: Nudix hydrolases form a protein family whose function is to hydrolyse intracellular nucleotides and so regulate their levels and eliminate potentially toxic derivatives. The genome of the radioresistant bacterium Deinococcus radiodurans encodes 25 nudix hydrolases, an unexpectedly large...

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Detalles Bibliográficos
Autores principales: Fisher, David I, Cartwright, Jared L, Harashima, Hideyoshi, Kamiya, Hiroyuki, McLennan, Alexander G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC428907/
https://www.ncbi.nlm.nih.gov/pubmed/15147580
http://dx.doi.org/10.1186/1471-2091-5-7