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The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females

BACKGROUND: BRCA1 promoter methylation has been detected in DNA from peripheral blood cells of both breast cancer patients and cancer-free females. However, the pathological significance of this epigenetic change in white blood cells (WBC) remains an open question. In this study, we hypothesized tha...

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Detalles Bibliográficos
Autores principales: Al-Moghrabi, Nisreen, Nofel, Asmaa, Al-Yousef, Nujoud, Madkhali, Safia, Bin Amer, Suad M, Alaiya, Ayodele, Shinwari, Zakia, Al-Tweigeri, Taher, Karakas, Bedri, Tulbah, Asma, Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289167/
https://www.ncbi.nlm.nih.gov/pubmed/25403427
http://dx.doi.org/10.1186/1471-2407-14-830