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Selective Internal Radiation Therapy (SIRT) with yttrium-90 resin microspheres plus standard systemic chemotherapy regimen of FOLFOX versus FOLFOX alone as first-line treatment of non-resectable liver metastases from colorectal cancer: the SIRFLOX study

BACKGROUND: In colorectal cancer (CRC), unresectable liver metastases are linked to poor prognosis. Systemic chemotherapy with regimens such as FOLFOX (combination of infusional 5-fluorouracil, leucovorin and oxaliplatin) is the standard first-line treatment. The SIRFLOX trial was designed to assess...

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Detalles Bibliográficos
Autores principales: Gibbs, Peter, Gebski, Val, Van Buskirk, Mark, Thurston, Kenneth, Cade, David N, Van Hazel, Guy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289171/
https://www.ncbi.nlm.nih.gov/pubmed/25487708
http://dx.doi.org/10.1186/1471-2407-14-897