Diversity-oriented synthesis and activity evaluation of substituted bicyclic lactams as anti-malarial against Plasmodium falciparum

BACKGROUND: Malaria remains the world’s most important devastating parasitic disease. Of the five species of Plasmodium known to infect and cause human malaria, Plasmodium falciparum is the most virulent and responsible for majority of the deaths caused by this disease. Mainstream drug therapy targe...

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Detalles Bibliográficos
Autores principales: Sharma, Vijeta, Agarwal, Shalini, Madurkar, Sanjay M, Datta, Gaurav, Dangi, Poonam, Dandugudumula, Ramu, Sen, Subhabrata, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289231/
https://www.ncbi.nlm.nih.gov/pubmed/25431142
http://dx.doi.org/10.1186/1475-2875-13-467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289231/
https://www.ncbi.nlm.nih.gov/pubmed/25431142
http://dx.doi.org/10.1186/1475-2875-13-467

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