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Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis

BACKGROUND: Pancreatic cancer is one of the deadliest human malignancies, with few therapeutic options. Re-activation of embryonic signaling pathways is commonly in human pancreatic cancer and provided rationale to explore inhibition of these pathways therapeutically. Notch signaling is important du...

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Detalles Bibliográficos
Autores principales: Thomas, Marsha M, Zhang, Yaqing, Mathew, Esha, Kane, Kevin T, Maillard, Ivan, Pasca di Magliano, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289235/
https://www.ncbi.nlm.nih.gov/pubmed/25416148
http://dx.doi.org/10.1186/1471-2407-14-862