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Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis
BACKGROUND: Pancreatic cancer is one of the deadliest human malignancies, with few therapeutic options. Re-activation of embryonic signaling pathways is commonly in human pancreatic cancer and provided rationale to explore inhibition of these pathways therapeutically. Notch signaling is important du...
Autores principales: | Thomas, Marsha M, Zhang, Yaqing, Mathew, Esha, Kane, Kevin T, Maillard, Ivan, Pasca di Magliano, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289235/ https://www.ncbi.nlm.nih.gov/pubmed/25416148 http://dx.doi.org/10.1186/1471-2407-14-862 |
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