Modification of topoisomerases in mammospheres derived from breast cancer cell line: clinical implications for combined treatments with tyrosine kinase inhibitors

BACKGROUND: Accumulating evidences suggest that tumors are driven by a small population of cells, termed “cancer stem cells” (CSCs), which may be resistant to current therapeutic approaches. In breast carcinoma, the CSCs have been identified as a CD44(+)/CD24(−) cell population. These rare cells are...

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Detalles Bibliográficos
Autores principales: Peleg, Refael, Romzova, Marianna, Kogan-Zviagin, Inga, Apte, Ron N, Priel, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289278/
https://www.ncbi.nlm.nih.gov/pubmed/25472619
http://dx.doi.org/10.1186/1471-2407-14-910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289278/
https://www.ncbi.nlm.nih.gov/pubmed/25472619
http://dx.doi.org/10.1186/1471-2407-14-910

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