Cargando…
Immune checkpoint receptors in regulating immune reactivity in rheumatic disease
Immune checkpoint regulators are critical modulators of the immune system, allowing the initiation of a productive immune response and preventing the onset of autoimmunity. Co-inhibitory and co-stimulatory immune checkpoint receptors are required for full T-cell activation and effector functions suc...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289356/ https://www.ncbi.nlm.nih.gov/pubmed/25606596 http://dx.doi.org/10.1186/s13075-014-0469-1 |