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Immune checkpoint receptors in regulating immune reactivity in rheumatic disease

Immune checkpoint regulators are critical modulators of the immune system, allowing the initiation of a productive immune response and preventing the onset of autoimmunity. Co-inhibitory and co-stimulatory immune checkpoint receptors are required for full T-cell activation and effector functions suc...

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Detalles Bibliográficos
Autores principales: Ceeraz, Sabrina, Nowak, Elizabeth C, Burns, Christopher M, Noelle, Randolph J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289356/
https://www.ncbi.nlm.nih.gov/pubmed/25606596
http://dx.doi.org/10.1186/s13075-014-0469-1