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Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models

BACKGROUND: Standard chemotherapy in unresectable biliary tract carcinoma (BTC) patients is based on gemcitabine combined with platinum derivatives. However, primary or acquired resistance is inevitable and no second-line chemotherapy is demonstrated to be effective. Thus, there is an urgent need to...

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Detalles Bibliográficos
Autores principales: Peraldo-Neia, Caterina, Cavalloni, Giuliana, Soster, Marco, Gammaitoni, Loretta, Marchiò, Serena, Sassi, Francesco, Trusolino, Livio, Bertotti, Andrea, Medico, Enzo, Capussotti, Lorenzo, Aglietta, Massimo, Leone, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289395/
https://www.ncbi.nlm.nih.gov/pubmed/25479910
http://dx.doi.org/10.1186/1471-2407-14-918