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Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid - short RadioTherapy - rectum 3rd trial)

BACKGROUND: Locally advanced rectal cancer (LARC) is a heterogeneous group of tumors where a risk-adapted therapeutic strategy is needed. Short-course radiotherapy (SCRT) is a more convenient option for LARC patients than preoperative long-course RT plus capecitabine. Histone-deacetylase inhibitors...

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Detalles Bibliográficos
Autores principales: Avallone, Antonio, Piccirillo, Maria Carmela, Delrio, Paolo, Pecori, Biagio, Di Gennaro, Elena, Aloj, Luigi, Tatangelo, Fabiana, D’Angelo, Valentina, Granata, Cinzia, Cavalcanti, Ernesta, Maurea, Nicola, Maiolino, Piera, Bianco, Franco, Montano, Massimo, Silvestro, Lucrezia, Terranova Barberio, Manuela, Roca, Maria Serena, Di Maio, Massimo, Marone, Pietro, Botti, Gerardo, Petrillo, Antonella, Daniele, Gennaro, Lastoria, Secondo, Iaffaioli, Vincenzo R, Romano, Giovanni, Caracò, Corradina, Muto, Paolo, Gallo, Ciro, Perrone, Francesco, Budillon, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289397/
https://www.ncbi.nlm.nih.gov/pubmed/25421252
http://dx.doi.org/10.1186/1471-2407-14-875