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Fate and plasticity of the epidermis in response to congenital activation of BRAF

Determining the developmental consequences of activated RAS and its downstream effectors is critical to understanding several congenital conditions caused by either germline or somatic mutations of the RAS pathway. Here we demonstrate that embryonic activation of BRAF in mouse ectoderm triggers both...

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Detalles Bibliográficos
Autores principales: Krishnaswami, Suguna R., Kumar, Shantanu, Ordoukhanian, Phillip, Yu, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289449/
https://www.ncbi.nlm.nih.gov/pubmed/25202828
http://dx.doi.org/10.1038/jid.2014.388