The Role of Endothelin-1 and Endothelin Receptor Antagonists in Inflammatory Response and Sepsis

Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a vasoconstrictive action, ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species. It is claimed...

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Detalles Bibliográficos
Autores principales: Kowalczyk, Agata, Kleniewska, Paulina, Kolodziejczyk, Michal, Skibska, Beata, Goraca, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289534/
https://www.ncbi.nlm.nih.gov/pubmed/25288367
http://dx.doi.org/10.1007/s00005-014-0310-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289534/
https://www.ncbi.nlm.nih.gov/pubmed/25288367
http://dx.doi.org/10.1007/s00005-014-0310-1

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