Improvement of SMN2 Pre-mRNA Processing Mediated by Exon-Specific U1 Small Nuclear RNA

Exon-specific U1 snRNAs (ExSpe U1s) are modified U1 snRNAs that interact with intronic sequences downstream of the 5′ splice site (ss) by complementarity. This process restores exon skipping caused by different types of mutation. We have investigated the molecular mechanism and activity of these mol...

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Detalles Bibliográficos
Autores principales: Dal Mas, Andrea, Rogalska, Malgorzata Ewa, Bussani, Erica, Pagani, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289686/
https://www.ncbi.nlm.nih.gov/pubmed/25557785
http://dx.doi.org/10.1016/j.ajhg.2014.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289686/
https://www.ncbi.nlm.nih.gov/pubmed/25557785
http://dx.doi.org/10.1016/j.ajhg.2014.12.009

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