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Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

Atopic dermatitis and psoriasis are the two most common immune-mediated inflammatory disorders affecting the skin. Genome-wide studies demonstrate a high degree of genetic overlap, but these diseases have mutually exclusive clinical phenotypes and opposing immune mechanisms. Despite their prevalence...

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Detalles Bibliográficos
Autores principales: Baurecht, Hansjörg, Hotze, Melanie, Brand, Stephan, Büning, Carsten, Cormican, Paul, Corvin, Aiden, Ellinghaus, David, Ellinghaus, Eva, Esparza-Gordillo, Jorge, Fölster-Holst, Regina, Franke, Andre, Gieger, Christian, Hubner, Norbert, Illig, Thomas, Irvine, Alan D., Kabesch, Michael, Lee, Young A.E., Lieb, Wolfgang, Marenholz, Ingo, McLean, W.H. Irwin, Morris, Derek W., Mrowietz, Ulrich, Nair, Rajan, Nöthen, Markus M., Novak, Natalija, O’Regan, Grainne M., Schreiber, Stefan, Smith, Catherine, Strauch, Konstantin, Stuart, Philip E., Trembath, Richard, Tsoi, Lam C., Weichenthal, Michael, Barker, Jonathan, Elder, James T., Weidinger, Stephan, Cordell, Heather J., Brown, Sara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289690/
https://www.ncbi.nlm.nih.gov/pubmed/25574825
http://dx.doi.org/10.1016/j.ajhg.2014.12.004